Diffusion-weighted MRI in acute stroke within the first 6 hours. 1.5 or 3.0 Tesla?
Neurology. 2010 May 12. [Epub ahead of print]
Rosso C, Drier A, Lacroix D, Mutlu G, Pires C, Lehéricy S, Samson Y, Dormont D.
Rosso C, Drier A, Lacroix D, Mutlu G, Pires C, Lehéricy S, Samson Y, Dormont D.
From the AP-HP, Urgences Cérébro-Vasculaires (C.R., G.M., C.P., Y.S.), and AP-HP, Service de Neuroradiologie (A.D., D.L., S.L., D.D.), Université Pierre et Marie Curie, Paris VI, Hôpital Pitié-Salpêtrière, Paris, France.
Abstract
OBJECTIVES: To compare the sensitivity and specificity of 1.5-T and 3.0-T diffusion-weighted MRI (DWI) to detect hyperacute ischemic stroke lesions. METHODS: We blindly reviewed the DWI of 135 acute stroke patients and 34 controls performed at 1.5 T (n = 108) or 3.0 T (n = 61). The stroke patients all had subsequently proved carotid territory ischemic stroke and were imaged within the first 6 hours after stroke onset. Four readers (2 neuroradiologists and 2 stroke neurologists) blinded to clinical data and magnetic field strength recorded the presence of ischemic lesions on DWI and apparent diffusion coefficient (ADC) maps if necessary. Sensitivity, specificity, and false-negative rates were computed. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and DWI contrasts were calculated at both field strengths. RESULTS: The accuracy of DWI in stroke diagnosis was superior at 1.5 T (98.8%) than at 3.0 T (90.9%, p = 0.03). The sensitivity decreased from 99.1% at 1.5 T to 92.5% at 3.0 T (p = 0.06) and the specificity from 97.8% to 84.1% (p = 0.002). ADC map readings did not improve accuracy, sensitivity, or specificity. The false-negative rate was 0.6% at 1.5 T and 6.1% at 3.0 T. Type of readers, stroke severity, and type of the coil did not affect diagnosis value. SNR and CNR were significantly higher at 3 T (p < 0.0001) but DWI contrast was lower (p = 0.04). CONCLUSIONS: Blind reading by 4 experts of a large series of images shows that 1.5-T diffusion-weighted MRI (DWI) is better than 3.0-T DWI for the imaging of hyperacute stroke during the therapeutic window of thrombolysis.Vaya, vaya. Seguimos con la línea de artículos ligeramente sorprendentes, aunque no tanto. O sea que la resonancia de 3.0 T no es tan buena como el viejo cacharro de 1.5 T para el infarto hiperagudo. Espero que no empiecen a salir publicaciones de este tipo para otros tipos de exploraciones o situaciones clínicas. Aunque soy escéptico por naturaleza. Estoy seguro, no obstante, de que el mayor número de artículos defenderá los avances y progresos que con toda seguridad se van a obtener de la nueva máquina, pero se agradece una bocanada de aire fresco de gente con capacidad crítica que compense el efecto "¡ta-chan!" de la novedad tecnológica. Aprovecho para recordaros que si queréis opinar o discrepar o advertir que vuestros datos no coinciden con los de los autores del artículo, podéis hacerlo enviando un comentario.
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